INVERSOLAB

Exploring the interplay of blood vessel,
immunology, and chronic inflammation

LABMISSION

Navigating Complexity: Merging Vascular Biology, Immunology, and Spatial Transcriptomics to Forge Scientific Progress

Welcome to InversoLab, where we explore the intricate interplay of vascular biology, immunology, and chronic inflammation. Our interdisciplinary team of scientists is dedicated to unraveling the complexities of biological processes within specific anatomical environments, driving transformative discoveries in biomedical science.

At the core of our mission lies a fusion of cutting-edge microscopy and spatially-resolved multi-omics with a traditional pathologist’s approach to biological questions, enabling us to expand the boundaries of basic and clinical understanding. We focus on deciphering how blood vessels shape organ compartmentalization and drive the progression of metabolic and viral diseases.

6 RESEARCHERS

Our lab has six experts who use advanced imaging technology to research nanoscale phenomena.

3 ACTIVE PROJECTS

Our lab researches electron microscopy with three active projects.

15 PAPER PUBLICATIONS

Their research, presented internationally, impacts medicine, energy, and electronics, and advances material and biological sciences.

LABRESEARCH

Navigating Liver's Complexity: Unraveling Chronic Disease Pathophysiology

The liver is a marvel of functional complexity, structured into specialized units known as liver lobules delineated by a remarkable spatial compartmentalization orchestrated by a unique vascular architecture. Blood, coursing through both the hepatic artery and portal vein, converges within the liver’s capillary network before exiting through the centrilobular vein. Beyond their architectural and circulatory role, these blood vessels wield significant influence, extending an instructive hand to neighbouring cells and establishing distinct peri-central and periportal areas. Indeed, vascular endothelial cells orchestrate a symphony of diverse gene expressions along the lobular axis, shaping what we term “lobular zonation.” This intricate process involves a substantial portion of the genome expressed by hepatocytes and parenchymal cells. At InversoLab our current focus lies in deciphering the complexities of vascular control within liver lobules and its pivotal role in chronic disease progression.

LABPUBBLICATIONS

Discover Insights from Our Latest Research Endeavors

Engage with the latest findings from our interdisciplinary research endeavors, spanning vascular biology, immunology, spatial transcriptomics, and liver pathobiology. Our curated collection offers insights into the intricate mechanisms underlying health and disease, providing valuable contributions to the scientific community. Navigate through our comprehensive repository of papers to explore the frontiers of biomedical science. Visit our dedicated section on scientific publications and immerse yourself in the world of cutting-edge research.

At the core of our mission lies a fusion of cutting-edge microscopy and spatially-resolved multi-omics with a traditional pathologist’s approach to biological questions, enabling us to expand the boundaries of basic and clinical understanding. We focus on deciphering how blood vessels shape organ compartmentalization and drive the progression of metabolic and viral diseases.